Title: AI-based Predictive Modelling and Molecular Enumeration against Lung Cancer
SHORT INTRODUCTION
Hi, Thanks for visiting my profile here!
I joined Computational Intelligence and Bioinformatic lab as a doctoral student in September 2021 and the youngest member of the lab. I completed my BSc (Hons) degree in Plant Sciences from the University of Delhi and then was admitted to Jamia Millia Islamia and obtained my master's degree in Bioinformatics in June 2020. I got myself great exposure to Genomics (WGS, WES) and Proteomics (computer-aided drug design) using programming sets and some tools/suits while working in a top few Indian institutions like ICGEB, IARI, Jamia Hamdard and SRM University.
MOTIVATION
An enthusiastic and self-motivated scholar, working on molecular enumeration and AI-based
predictive modelling to deliver a drug candidate (formulation) that can bind (only) to multiple
lung cancer targets and choke the identified pathways. Collaborating (and open to) with experimentalists/industry with expertise in lung cancer to deliver an enumerated formulation to cure lung cancer at a significantly cheaper state.
SUPERVISOR
- Dr. Khalid Raza , Assistant Professor, Department of Computer Science, Faculty of Natural Sciences, Jamia Millia Islamia, New Delhi-110025.
PATENT
- DdpMPyPEPhU: A single capsule against seven deadliest cancers (file no: yet to update)
AWARDS/ACHIEVEMENTS
- Awarded fellowship for six months from Department of Biotechnology, Govt of India as 'DBT-Studentship' at ICAR-Indian Agricultural Research Institute, New Delhi to carry out the master's dissertation project, from 15th January to 15th July 2020.
- Best Oral presentation award in 'Interdisciplinary Science Conference: Big Data and Computational Biology' organised by CIRBSc, Jamia Millia Islamia, New Delhi 21-22oct 2019.
- Best Poster presenter award in National Conference on 'Conservation, cultivation and Sustainable use of Medicinal and Aromatic Plants (CCSMAP)' at Manav Rachna International Institute of Research and Studies (MRIIRS), 21-22 February 2019.
- Awarded two-month fellowship from Department of Biotechnology, Govt of India as 'DBT-Studentship' at Jamia Hamdard, New Delhi, to carry out the comparative analysis on Plasmodium vivax, from March to April 2019.
- 1st prize in Working model presentation in Seminar and Working model presentation, on 13 April 2018 'PARIVARTAN 2K18' Department of Environmental science and NSS, Sri Aurobindo College, University of Delhi.
- Felicitated in 26th World Environmental Congress- World Environmental and Ecology Development (WEED) (Greening of Education, Employment, Environment, Empowerment, and Entrepreneurship), (Affiliated to United Nations under ECOSOC, UNDPI, UNICEF, UNESCO ), 8th November 2017 at Indian International Centre, New Delhi.
- 2nd prize in Explico - Know Your Green in 'SANJEEVANI' October 2016, Department of Botany, Deshbandhu College, University of Delhi.
- Best poster award in ICSSR sponsored National Seminar on 'Emerging Issues of Climate Changes: Sustainability and Economic Implications' on 21st-22nd October 2016, conducted by Sri Aurobindo College, University of Delhi.
- Awarded fellowship for the Research/Innovation Project Titled: Food for future: Studies on the nutritional value of Fagopyrum esculentum (Kuttu) - a pseudo-cereal and efficacy of weed-based botanicals against its root rot disease from 1st September 2015 to 31st August 2016 at the University of Delhi.
RESEARCH TRAINING/ EXPERIENCE
- Jamia Millia Islamia, New Delhi [September 2021-Present]
PhD Scholar (C/o- Dr Khalid Raza)
Responsibilities: AI-based Predictive Modelling and Molecular Enumeration against Lung Cancer
- SRM University Delhi-NCR, Sonepat, Haryana [03Nov 2020 - 02 Nov 2021]
Project Assistant (SERB funded with Project ID: CVD/2020/000447) (C/o- Dr MK Yadav)
Responsibilities: Drug repurposing against key COVID-19 Drug Targets using advance Machine Learning based algorithms
- Jamia Millia Islamia, New Delhi [June 2020- October 2021]
Project Assistant (Volunteer; In collaboration with AIIMS, New Delhi) (C/o- Dr Khalid Raza)
Responsibilities: Nanodrug designing; Molecular modelling, docking, and Dynamics Simulation
- ICAR- Indian Agricultural Research Institute [Jan-June 2020]
DBT-Studentship (Fellowship awarded for completion of Dissertation at ICAR- AKMU-IARI) (C/o- Prof A. K. Mishra)
Responsibilities: Denovo assembly, annotation of Ralstonia solanacearum Strain- UTT-25 (Bacterial whole genome)
- International Center for Genetic Engineering and Biotechnology [May-Dec 2019]
Research Trainee (NIC- PMB Group- C/o- Prof Tanushri Kaul)
Responsibilities: NGS data analysis for Whole Genome Sequence and complete chloroplast genome of Vigna umbellata
- Jamia Hamdard University [MARCH-APRIL 2019]
DBT- Studentship (DBT-BIF) (C/o- Prof Shakir Ali)
Responsibilities: Comparative Genomics study of Plasmodium vivax and P. falciparum
- International Center for Genetic Engineering and Biotechnology [Jan-feb2019]
Research Trainee (NIC-PMB Group) (C/o- Prof Tanushri Kaul)
Responsibilities: Plant tissue culture, different media and hormone preparation
- University of Delhi [15 Sept 2015 - 15 Oct 2016]
Research Trainee University of Delhi Innovation project with project ID- DBC-301, (C/o- Prof Minakshi Prejneshu, Rtd. and Dr Niti Pathak)
Responsibilities: Food for future: Studies on the nutritional value of Kuttu (Fagopyrum esculentum) - a pseudo cereal and efficacy of weed-based botanicals against its Root-rot)
RESEARCH INTEREST
- Multitargetted drug designing
- AI-based predictive modelling
- Molecular Modelling
- Molecular Dynamics Simulation
- Computer Aided Drug Designing
- Cancer Genomics
- NGS Data Analysis
PUBLICATIONS
Published Book Chapters
- Tripathi, M. K., Ahmad, S., Tyagi, R., Dahiya, V., & Yadav, M. K. (2022). Fundamentals of molecular modeling in drug design. In Computer Aided Drug Design: From Ligand-Based Methods to Structure-Based Approaches (pp. 125-155), Elsevier. https://doi.org/10.1016/B978-0-323-90608-1.00001-0
- Khan, F.N., Khanam, A.A., Ramlal, A. and Ahmad, S., 2021. A review on predictive systems and data models for covid-19. In Computational Intelligence Methods in COVID-19: Surveillance, Prevention, Prediction and Diagnosis (pp. 123-164), Springer. https://doi.org/10.1007/978-981-15-8534-0_7
- Ahmad, S., Chitkara, P., Khan, F.N., Kishan, A., Alok, V., Ramlal, A. and Mehta, S., 2021. Mobile Technology Solution for COVID-19: Surveillance and Prevention. In Computational Intelligence Methods in COVID-19: Surveillance, Prevention, Prediction and Diagnosis (pp. 79-108), Springer Singapore. https://doi.org/10.1007/978-981-15-8534-0_5
- Ramlal, A., Ahmad, S., Kumar, L., Khan, F.N., Chongtham, R., 2021. From molecules to patients: The clinical applications of biological databases and electronic health record. Translational Bioinformatics in Healthcare and Medicine pp. 107-125. https://doi.org/10.1016/B978-0-323-89824-9.00009-4
- Khan, F.N., Ahmad, S. and Raza, K., 2021. Clinical Applications of Next-generation sequence analysis in Acute Myelogenous Leukemia (AML), Translational Bioinformatics Applications in Healthcare, p.41. https://dx.doi.org/10.1201/9781003146988-4
- Bharti, J., Mehta, S., Ahmad, S., Singh, B., Padhy, A.K., Srivastava, N. and Pandey, V., 2021. Mitogen-activated protein kinase, plants, and heat stress. In Harsh Environment and Plant Resilience (pp. 323-354). Springer, Cham. https://doi.org/10.1007/978-3-030-65912-7_13
- Balasubramanian, B., Ahmad, S., Alok, V., Khan, F.N., Anand, K., Mehta, S., Easwaran, M., Meyyazhagan, A. and Saravanan, M., 2021. Exosomes as an emerging nanoplatform for functional therapeutics. Handbook on Nanobiomaterials for Therapeutics and Diagnostic Applications, pp.483-498. https://doi.org/10.1016/B978-0-12-821013-0.00002-7
- Karwasra R., Khanna K., Singh S., Ahmad S., Verma S. (2022) The Incipient Role of Computational Intelligence in Oncology: Drug Designing, Discovery, and Development. In: Raza K. (eds) Computational Intelligence in Oncology. Studies in Computational Intelligence, vol 1016. Springer, Singapore. https://doi.org/10.1007/978-981-16-9221-5_21
COURSES STUDIED DURING PRE-PhD
PCS1.1: Scientific Research Methodology
73/100
PCS1.2: Research Skills, Ethics and Publications
80/100
PCS1.3: Literature Review and Term Paper
84/100
PCS1.4.2: Machine Learning Techniques in Bioinformatics
90/100
1st rank in the Pre-PhD coursework
TEACHING ASSISTANTSHIP
WORKSHOP ATTENDED
- "Cloud-based Hands-on Workshop on Molecular Docking, Pharmacophore Modeling and Machine Learning", 15-16t March 2022, organised by the Bioinformatics Division, ICMR - National Institute of Cancer Prevention and Research, and Schrodinger Inc, Noida.
- International Workshop on "Discovery of Vaccines and Drugs for Infectious Diseases", 06-09th December 2021, International Centre for Genetic Engineering and Biotechnology, New Delhi.
- AI workshop 2021, "7 days International Workshop on Artificial Intelligence", 15th-21st November 2021. Co-organised by AiCHEF and St Claret College, Bengaluru.
- Cloud-based Hands-on Workshop "2-days Cloud-based Hands-on Workshop: Computational SBDD & MD Simulations", 02 to 3 September 2021. Co-organised by SRM University (Delhi-NCR) and Schrodinger Inc, Sonepat, Haryana.
- Hands-on online workshop on "Quantitative genetics genomics and plant breeding", 23rd-27 November 2020, Department of Biotechnology, Vignan's Foundation for Science, Technology & Research, Vadlamudi-522213, Guntur, Andhra Pradesh, India.
- DBT Apex Biotechnology Information Centre (DBT-ABTIC) workshop on "Advanced Structural Bioinformatics", 18th - 21st November 2019, International Centre for Genetic Engineering and Biotechnology, New Delhi.
- One-day workshop on "Deep learning and IoT using MATLAB" on October 3, 2019, Dept. of Computer Science, Jamia Millia Islamia, New Delhi.
- "BioTecNika Schrodinger Joint Workshop on Computer-Aided Drug Discovery" organised by Biotecnika info Pvt. Ltd on 22nd July-2nd August 2019.
- DBT-BIF workshop on "Application of Artificial Intelligence in Modern Biology" 28-29 March 2019, International Centre for Genetic Engineering and Biotechnology, New Delhi.
- 9th DBT-BIF sponsored National Workshop on "Translational Bioinformatics: Guinness Book Recording to Digital Era-(NWTB: GB2DE-2019)" 6th-7th March 2019 BIF Centre, Dept. of Computer Science Jamia Millia Islamia, New Delhi.
- DBT GOI sponsored National level workshop on "INTERACTIVE NGS DATA ANALYSIS" from 15th -17th November 2018, Bioinformatics Centre, Northeastern Hill University (NEHU), Shillong.
CONFERENCES/SEMINAR ATTENDED
- One Day virtual seminar on "Intellectual Property Rights" (on National Science Day), organised by CIF, Jamia Millia Islamia University, New Delhi. 28 February 2022.
- 3rd ICGA 2022 Virtual Conference entitled "Biobanking to Omics: Collecting the Global Experience" January 13-14, 2022.
- Economic botany and plant genetic resources: National Perspective, Deshbandhu College, University of Delhi, New Delhi, 18 January 2022.
- Computational Biology connecting demand of Science, ISCBSC- RSG India Student symposium 2019, Jawaharlal Nehru University (JNU) New Delhi, 22 November 2019.
- Young Scientist Conference- India International Science Festival (YSC-IISF), 2019, (Fully funded by DST and other funding agencies , GoI) Kolkata, India, 5-7 Nov 2019.
- Interdisciplinary Science Conference: Big Data and Computational Biology organised by Centre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, New Delhi 21-22oct 2019.
- DST-PURSE sponsored National Seminar on Biophysics (Biophysica 2019), Centre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia New Delhi.
- Mini-symposium on "Tracking Antimicrobial Drug Resistance Tuberculosis: Novel Approaches" at the Vallabhbhai Patel Chest Institute, University of Delhi.
- 20th Distinguished Lecture on "Structure-guided Fragment-based drug designing for Cancer and Tuberculosis: Fighting the Emergence of Resistance" by Sir Tom Blundell at Jamia Hamdard 20th March 2019.
- Symposium on "Avenues in Plants Sciences: A Hope for Sustainable Future" at Deshbandhu College, University of Delhi 8-9th March 2019.
- National Conference on "Conservation, cultivation and Sustainable use of Medicinal and Aromatic Plants (CCSMAP)", at MRIIRS, 21-22 February 2019.
- Fourth National Symposium on "Environment: Green Technology for Environmental Sustainability" 25 September 2018 Deshbandhu College, University of Delhi.
- National Science Congress association Delhi Chapter at Zakir Hussain Delhi College "Consciousness and Artificial Intelligence" along with Model presentation 25th October 2017.
- Seminar and Working model presentation, on 13 April 2018 "PARIVARTAN 2K18" Department of Environmental science and NSS, Sri Aurobindo College, University of Delhi.
- 26th World Environmental Congress; World Environmental and Ecology Development (WEED) (Greening of Education, Employment, Environment, Empowerment, and Entrepreneurship) 8th November 2017 at Indian International Centre.
- Two days seminar and poster presentation "Trends in Nanobiotechnology" 'BIOTIKOS 2017', 28-29 September 2017 Department of Biotechnology, TERI School of Advanced Sciences.
- Conference on "Growth control in development and disease: From Fruit fly to Human Cancer" on 7th October 2016, National Institute of Immunology, New Delhi
- National Conference on "Galapagos Island and Darwin's Theory of Evolution" on 6th October 2016, National Institute of Immunology, New Delhi
- ICSSR sponsored seminar "Emerging Issues of Climate change: Sustainability and Economic implications" conducted in Sri Aurobindo College, the University of Delhi on 21-22 Oct 2016.
- Environmental Concerns of the 21st century: Indian global context at Zakir Hussain Delhi College, University of Delhi.
CONFERENCES PAPERS
- Ankita Sahu, Khalid Raza, Shaban Ahmad, Saurabh Varma 'In silico study of aromatase inhibitors using computer-aided drug design' in World Congress on Reproductive Health with Emphasis on Reproductive Cancers, Infertility and Assisted Reproduction & 30th Annual Meeting of the Indian Society for the Study of Reproduction and Fertility (ISSRF2020), at Shri Mata Vaishno Devi University Katra, Jammu and Kashmir- India, 14-16 February.
- Shaban Ahmad 'Rice Bean (Vigna umbellata) draft genome sequence: unravelling the late flowering and unpalatability related genomic resources' in Young Scientist Conference India International Science Festival (YSC- IISF), Kolkata, India, 05-07 November 2019.
- Shaban Ahmad 'Deep learning and Artificial intelligence in Biological sciences' in Interdisciplinary Science Conference: Big Data and Computational Biology organized by Centre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, New Delhi 21-22oct 2019.
- Niti Pathak Bhaduri, Asani Bhaduri, Meenakshi Prajneshu, Faran Salik, A. Ramlal, Awantika Kumari, Laxman, Manshi Gaur, Sonia Suri, Shaban Ahmad, Aman Sharma 'Study of Bioactive component in Buckwheat and in-silico analysis of fagopyritol synthase' in 'Emerging Issues of Climate change: Sustainability and Economic implications' at Sri Aurobindo College, University of Delhi on 21-22 October 2016 Delhi India.
- Shaban Ahmad 'Rice Bean (Vigna umbellata) draft genome sequence: unravelling the late flowering and unpalatability related genomic resources' in Interdisciplinary Science Conference: Big Data and Computational Biology organized by Centre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, New Delhi 21-22oct 2019.
- Shaban Ahmad, Niti Pathak, Laxman Kumar, MeenakshiPrajneshu, 'Efficacy of Weed based botanicals against Rhizoctonia root rot in Buckwheat (Fagopyrum sp.) in 1st National Conference on 'Neglected and Underutilized Crop Species for Food, Nutrition, Energy and Environment' at National Institute of Plant Genome Research (NIPGR) New Delhi August 02 2019.
- A. Ramlal, Laxman Kumar, Pooja, Tanuja, Loveleen Kaur and Shaban Ahmad, 'Sustainable Agriculture and Global Food Security: Perspective, importance and Opinion' in Symposium on 'Avenues in Plants Sciences: A Hope for Sustainable Future' at Deshbandhu College, University of Delhi 8-9th March 2019.
- Niti Pathak, Shaban Ahmad, Meenakshi Prajneshu, 'Buckwheat (Kuttu): As food, good health and Medicine' in National Conference on 'Conservation, cultivation and Sustainable use of Medicinal and Aromatic Plants (CCSMAP)', at Manav Rachna International Institute of Research and Studies (MRIIRS), 21-22 February 2019.
- Shaban Ahmad, A Ramlal, Laxman Kumar, 'Biofuels: A sustainable approach of Futuristic Energy' in National Conference on 'Trends in Life Sciences and Biotechnology: Innovation Paradigms' at Maitreyi College University of Delhi, 19-20 February 2019.
- Shaban Ahmad, Biodiversity: Threats and Conservation in Fourth National Symposium on 'Environment: Green Technology for Environmental Sustainability' Deshbandhu College, University of Delhi September 25, 2018, Delhi India.
- Niti Pathak Bhaduri, Meenakshi Prajneshu, Sonia Suri, Shaban Ahmad, A. Ramlal 'Role of Nanobiotechnology in Enhancing Crop production' in 'Trends in Nanobiotechnology' at TERI University 28-29 September 2017 Delhi India.
- Niti Pathak Bhaduri, Asani Bhaduri, Meenakshi Prajneshu, Faran Salik, A. Ramlal, Awantika Kumari, Laxman, Manshi Gaur, Sonia Suri, Shaban Ahmad, Aman Sharma 'Study of Bioactive component in Buckwheat and in-silico analysis of fagopyritol synthase' in 'Emerging Issues of Climate change: Sustainability and Economic implications' at Sri Aurobindo College, University of Delhi on 21-22 October 2016 Delhi India.
TECHNICAL SKILLS
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